Abstract

In this study organic-inorganic hybrid nanoflowers were synthesized using methanolic extracts of the medicinal plants’ Rosa canina L. and Rubus sanctus Schreber together with copper ions (Cu2+). The synthesized plant extract based–inorganic hybrid nanoflowers (PE-ihNFs) of R.canina (Rc-ihNFs) and R.sanctus (Rs-ihNFs) were characterized by Energy-Dispersive X-ray (EDX), Fourier transform infrared spectrometry (FTIR) and Scanning Electron Microscopy (SEM), X-Ray Diffraction (XRD). Also, several enzymes were selected to determine the enzyme inhibitionactivities of the synthesized PE-ihNFs. For the first-time, enzymes (tyrosinase, α-amylase and α-glucosidase, acetyl and butyryl cholinesterase) inhibition activities of the PE-ihNFs and their plain plant extracts were evaluated in vitro assays. Results showed that the PE-ihNFs demonstrated better α-glucosidase & α-amylase enzyme inhibition activity compared to the plain extracts. These initial studies are promising for the synthesis of these hybrid nanoflowers containing plant extracts, which might have commercial applications in the pharmaceutical and dermo-cosmetics industries.

Keywords: hybrid nanoflowers, enzyme inhibitions, plants extract, phytocosmetics